The article focuses on analysis of Germany’s stance as regards transatlantic cooperation in the 21st century, presenting successively 1) main elements concerning the evolution of the transatlantic cooperation with special regard to Germany’s stance toward the U.S.; 2) controversies in Germany around working out provisions of the TTIP agreement; 3) the attitude of Christian Democrat-Liberal government towards the prospects of successful negotiations as well as the significance of fi nalizing the TTIP agreement. In evaluating Germany’s attitude as to the Transatlantic partnership the biggest emphasis has been devoted to Germany’s determinants and interests in its relations with the U.S. in political and socio-economic grounds. As regards controversies around future shape of TTIP agreement positions of CSU/CDU/SPD government, opposition parties in Bundestag as well as economic circles, trade unions, experts, scholars and non-governmental organizations have been taken into consideration. Basing on conducted opinion polls in the U.S. and in Germany in the final part of the study the attitudes of public opinion in both these states as for the crucial questions of Transatlantic cooperation have been presented between the EU and the U.S. There is ambivalence because generally supporting the signing of TTIP agreement between the EU and the U.S. the German society expresses stringent opposition to importing American genetically modified food to European markets. Changing social moods among German society on TTIP agreement’s provisions force CDU/CSU/SPD to declare enhanced readiness to European standards and the EU’s interests.