The article presents Russia’s reaction to the unrests in the Arab world which took place in 2011. Apparently, Russian Federation is one of the key actors in international relations, ergo analyzing so important events like the Arab Spring, Moscow’s reaction should be taken into account. The North Africa and Middle East are essential in global geopolitics, so Russian Federation had to take appropriate steps. Its reaction was determined by both internal and external factors. Russia’s Arab Spring strategy had to consider kind and scale of Russian interests in each Arab country dealing with unrests. Moreover, relations between Moscow and Washington also were highly important. These two elements, connected with Russian limited means, made it hard to develop right and clear strategy. In addition, Russian establishment had some justified fears about spreading to Russia and former Soviet republics in Central Asia. The following article comprises two parts. The first one is dedicated to the review of Russian reaction and activities towards revolts in the following Arab states: Tunisia, Egypt, Bahrain, Yemen, Libya and Syria. It contains Moscow diplomacy activities and statements of Russian political leaders and diplomats. Russian position and interests in the region of the North Africa and Middle East are explained in the second part of this article. After a short, historical outline, the author explained the role of the Arab world in Russian foreign policy and relation between its reaction to the Arab Spring and its political and economic interests.